JQ1-TCO

JQ1-TCO is the double bond E configuration of JQ1-TCO. JQ1-TCO (JQ1-trans-cyclooctene) is a derivative of JQ1 (HY-13030), an inhibitor of BET. JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo[1][2].

C31H37ClN6O3S

609.18

CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCCNC(OC4CC/C=C/CCC4)=O)=O)C5=NN=C(C)N25

Epigenetic Reader Domain

BRD4

99.95

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature