JSH-23 [CAS 749886-87-1]

JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS) -stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation[1].

[749886-87-1]

C16H20N2

240.34

NC1=CC(C)=CC=C1NCCCC2=CC=CC=C2

NF-κB

NF-κB

99.92

DMSO : ≥ 56 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H318, H400

H302, H318, H400