JTV-506 [CAS 170148-29-5]

JTV-506 is a potent ATP-sensitive potassium channel opener. JTV-506 inhibits Histamine -induced contraction of tracheal smooth muscle by activation of KATP channels. JTV-506 attenuates pulmonary vascular tone through its direct action on vascular smooth muscle cells. JTV-506 can be used for pulmonary hypertension research[1][2].

[170148-29-5]

C19H22N4O5

386.4

N#CC1=CC=C2C([C@@H](NC(C=C3)=NN(C)C3=O)[C@H](O)C(COC)(COC)O2)=C1

Potassium Channel

Room temperature