JYQ-194

JYQ-194 is a PROTAC degrader targeting human Parkinson's disease protein 7 (PARK7). JYQ-194 can be used in the study of cancer and neurodegenerative diseases. (Pink: PARK7 ligand ; Black: linker (HY-W017440) ; Blue: E3 ligase ligand (HY-10984) ).

C39H38FN11O8S

839.85

O=C([C@H]1CN(C#N)CC1)NC(S2)=NC3=C2CN(C(C4=C(F)C=CC(N5C=C(COCCOCCNC6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)N=N5)=C4)=O)CC3

PROTACs

98.05

DMSO : 25 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature