JZ19

JZ19 reduces the LDH and ROS levels, and exhibits antioxidant activity against oxygen-glucose deprivation (OGD) -induced cardiomyocyte injury. JZ19 reverses Isoproterenol -induced cardiomyocyte hypertrophy and apoptosis through PI3K-AKT-GSK3β signaling pathway. JZ19 alleviates Isoproterenol (HY-B0468) -induced heart failure in mouse models[1].

C22H25F3O10

506.42

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Akt; Apoptosis; GSK-3; PI3K

Room temperature