KAI-11101

Size 1 Each

SKU:QM-0009360

Price on request

Quote Datasheet SDS COA

Product Details

Description
KAI-11101 is the inhibitor for dual leucine zipper kinase (DLK, MAP3K12) with a Ki of 0.7 nM. KAI-11101 inhibits Paclitaxel -induced cJun phosphorylation (IC50=95 nM) and thus inhibits the activation of MAPK pathway. KAI-11101 is blood brain barrier penetrable and can be further investigated for its neuroprotective property[1].
Molecular Formula
C21H23F4N5O3
Molecular Weight
469.43
Smiles
O=C1C(N(CC)N=C2C3=CC(OC(F)F)=C(N)N=C3)=C2C=CN1[C@H]4[C@@H](OC)CC(F)(F)CC4
Target
MAP3K; p38 MAPK
Shipping Conditions
Room temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
1 EachQM-0009360	1 EachQM-0009360 Regular price ~~£0.00~~ Sale price £0.00/ea	£0.00	Quantity	Regular price ~~£0.00~~ Sale price £0.00/ea	£0.00

KAI-11101 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.