Kazinol B [CAS 99624-27-8]

Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research[1][2].

[99624-27-8]

C25H28O4

392.49

C/C(C)=C/CC1=C([C@H]2OC3=CC(O)=CC=C3CC2)C=C4C(OC(C)(C)C=C4)=C1O

Akt; AMPK; NO Synthase

AMPK

10 mM in DMSO

Room temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501