Keap1-Nrf2-IN-10 [CAS 2445349-54-0]

Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].

[2445349-54-0]

C25H22I2N4O7S2

808.4

COC1=CC(NC(CSC2=NC3=C(C=C(C=C3C(N2C4=CC=C(C=C4)S(N)(=O)=O)=O)I)I)=O)=CC(OC)=C1OC

Quinone Reductase; Reactive Oxygen Species (ROS)

10 mM in DMSO

Room temperature