Keap1-Nrf2-IN-5 [CAS 2696272-70-3]

Keap1-Nrf2-IN-5 (compound 1) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with an IC50 of 4.1 µM, Kd of 3.7 µM[1].

[2696272-70-3]

C23H30N4O6S

490.57

O=C([C@H](NC([C@H](NC([C@H]1N(C(C)=O)CCC1)=O)CO2)=O)CSCC3=CC=CC=C3C2=O)N(C)C

Keap1-Nrf2

10 mM in DMSO

Room temperature