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Keto-itraconazole [CAS 112560-33-5]
Keto-itraconazole [CAS 112560-33-5]
SKU:QM-0004327-01
£589.46 GBP
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Product Details
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Description
Keto-itraconazole (keto-ITZ) is a metabolism of Itraconazole with a potent inhibitor activity of CYP3A. Keto-itraconazole shows unbound IC50 value of 4.6 nM when coincubated with human liver microsomes and midazolam[1].
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CAS Number
[112560-33-5]
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Molecular Formula
C35H36Cl2N8O5
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Molecular Weight
719.62
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Smiles
O=C1N(N=CN1C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@@H]5O[C@](CN6N=CN=C6)(OC5)C7=CC=C(C=C7Cl)Cl)C(C)C(C)=O
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Target
Cytochrome P450
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Purity
98.4
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Keto-itraconazole [CAS 112560-33-5]
Keto-itraconazole is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.