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KGA-2727 [CAS 666842-36-0]

KGA-2727 [CAS 666842-36-0]

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SKU:QM-0140959-01

£489.83 GBP
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  • Description

    KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat) . KGA-2727 has antidiabetic efficacy[1].

  • CAS Number

    [666842-36-0]

  • Molecular Formula

    C26H40N4O8

  • Molecular Weight

    536.62

  • Smiles

    O=C(N)CCNCCCOC1=CC=C(CC2=C(C(C)C)NN=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(C)=C1

  • Target

    SGLT

  • Isoform

    SGLT1

  • Purity

    98.84

  • Solubility

    DMSO : 200 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic) |H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H319

  • Precautions

    H302, H319

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Variant Variant total Quantity Price Variant total
5 mgQM-0140959-01
5 mgQM-0140959-01
£489.83/ea
£0.00
£489.83/ea £0.00
10 mM - 1 mLQM-0140959-02
10 mM - 1 mLQM-0140959-02
£568.80/ea
£0.00
£568.80/ea £0.00
10 mgQM-0140959-03
10 mgQM-0140959-03
£777.78/ea
£0.00
£777.78/ea £0.00
25 mgQM-0140959-04
25 mgQM-0140959-04
£1,288.09/ea
£0.00
£1,288.09/ea £0.00
50 mgQM-0140959-05
50 mgQM-0140959-05
£1,744.92/ea
£0.00
£1,744.92/ea £0.00
100 mgQM-0140959-06
100 mgQM-0140959-06
£2,371.86/ea
£0.00
£2,371.86/ea £0.00

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KGA-2727 [CAS 666842-36-0]

KGA-2727 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.