KGP591 [CAS 3018962-69-8]

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SKU:QM-0071664

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Product Details

Description
KGP591 is a tubulin polymerization inhibitor (IC50 0.57 µM) . KGP591 induces significant G2/M stagnation, inhibits cell migration, disrupts microtubule structure and cell morphology in MDA-MB-231 cells. KGP591 shows antitumor activity in orthotopic model of kidney cancer (RENCA) [1].
CAS Number
[3018962-69-8]
Molecular Formula
C24H21NO5
Molecular Weight
403.43
Smiles
COC1=CC(C(C2=CNC3=CC(C4=CC=CC(O)=C4)=CC=C23)=O)=CC(OC)=C1OC
Target
Microtubule/Tubulin
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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KGP591 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.