Ki16198 [CAS 355025-13-7]

Ki16198 is a potent and orally active LPA receptor antagonist, the methyl ester of Ki16425. Ki16198 inhibits LPA1 and LPA3-induced inositol phosphate production with Ki values of 0.34 μM and 0.93 μM, respectively. Ki16198 is effective for pancreatic cancer tumorigenesis and metastasis in vivo[1].

[355025-13-7]

C24H25ClN2O5S

488.98

O=C(OC)CCSCC1=CC=C(C2=C(NC(OC(C3=CC=CC=C3Cl)C)=O)C(C)=NO2)C=C1

LPL Receptor

98.17

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature