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Ki20227 [CAS 623142-96-1]

Ki20227 [CAS 623142-96-1]

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SKU:QM-0083601-01

£106.00 GBP
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  • Description

    Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β) . Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction[1].

  • CAS Number

    [623142-96-1]

  • Molecular Formula

    C24H24N4O5S

  • Molecular Weight

    480.54

  • Smiles

    O=C(NC1=CC=C(C=C1OC)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC(C)C4=NC=CS4

  • Target

    C-Fms; c-Kit; PDGFR; VEGFR

  • Concentration

    10mM

  • Purity

    99.51

  • Solubility

    DMSO : 62.5 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
2 mgQM-0083601-01
2 mgQM-0083601-01
£106.00/ea
£0.00
£106.00/ea £0.00
5 mgQM-0083601-02
5 mgQM-0083601-02
£200.66/ea
£0.00
£200.66/ea £0.00
10 mM - 1 mLQM-0083601-03
10 mM - 1 mLQM-0083601-03
£209.16/ea
£0.00
£209.16/ea £0.00
10 mgQM-0083601-04
10 mgQM-0083601-04
£288.14/ea
£0.00
£288.14/ea £0.00
25 mgQM-0083601-05
25 mgQM-0083601-05
£514.13/ea
£0.00
£514.13/ea £0.00
50 mgQM-0083601-06
50 mgQM-0083601-06
£791.15/ea
£0.00
£791.15/ea £0.00
100 mgQM-0083601-07
100 mgQM-0083601-07
£1,229.77/ea
£0.00
£1,229.77/ea £0.00

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Ki20227 [CAS 623142-96-1]

Ki20227 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.