KRAS G12C-IN-72 [CAS 2326523-41-3]

KRAS G12C-IN-72 (Example 571) is a KRAS G12C inhibitor. KRAS G12C-IN-72 can be used as a target protein ligand to synthesize PROTACs, such as KRAS degrader-1. KRAS G12C-IN-72 can be used in cancer research[1].

[2326523-41-3]

C31H33ClFN7O2

590.09

ClC1=CC=CC2=C1C(N3CC4=NC(OC[C@@H]5CCCN5)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C4CC3)=CC=C2

Ligands for Target Protein for PROTAC; Ras

K-Ras

Room temperature