KRASG12D-IN-1

KRASG12D-IN-1 (compound 22) is a KRASG12D Inhibitor. KRASG12D-IN-1 has dose-dependent anti-tumor efficacy in the AsPC-1 xenograft mouse models with a tumor growth inhibition[1].

C34H28D2F4N6O2

632.65

FC1=C(C2=CN=C1C3=C4C(C#C)=C(C=CC4=CC(O)=C3)F)N=C(N=C2N5C[C@H](CC6)N[C@H]6C5)OC([2H])(C78CCCN7C/C(C8)=C(F)\F)[2H]

Ras

98.07

DMSO : 71.43 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature