KRASG12D-IN-2

KRASG12D-IN-2 (compound 28) is a KRASG12D Inhibitor. KRASG12D-IN-1 has dose-dependent anti-tumor efficacy in the AsPC-1 xenograft mouse models with a tumor growth inhibition[1].

C34H29D2F4N7O

631.66

FC1=C(C2=CN=C1C3=C4C(C#C)=C(C=CC4=CC(N)=C3)F)N=C(N=C2N5C[C@H](CC6)N[C@H]6C5)OC([2H])([2H])C78CCCN7C/C(C8)=C(F)\F

Ras

98.11

DMSO : 250 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature