KSL 128114 [CAS 2757292-12-7]

KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin[1].

[2757292-12-7]

C96H165N39O21

2201.59

N=C(N)NCCC[C@@H](NC(C)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(NCC(N[C@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](C(C)(C)C)C(N[C@@H](C2CCCCC2)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

SDCBP

10 mM in DMSO

Room temperature