KT2-962 [CAS 129648-96-0]

KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC50=500 nM) . KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases[1].

[129648-96-0]

C23H25ClNNaO5S2

518.02

O=S(C1=C2C=CC(C(C)C)=CC=C2C(CCCCNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)(O[Na])=O

Prostaglandin Receptor

TXA2/TP

Room temperature