KY-1044 [CAS 2489390-15-8]

Name: KY-1044 [CAS 2489390-15-8]
Brand: QuantiMol
SKU: QM-0202068-01
Price: 451.65 GBP
Availability: InStock

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SKU:QM-0202068-01

£451.65 GBP

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Product Details

Description
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 antibody targeting inducible costimulatory receptor (ICOS) . KY-1044 depletes ICOShigh cells via antibody-dependent cellular cytotoxicity (ADCC) through the engagement of FcgRIIIa. KY-1044 act as a costimulatory molecule on cells expressing lower ICOS levels, such as CD8+ TEff cells (through FcgR-dependent clustering) . KY-1044 exploit the differential expression of ICOS on T-cell subtypes to improve the intratumoral immune contexture and restore an antitumor immune response[1].
CAS Number
[2489390-15-8]
Smiles
[KY-1044]
Target
CD28
Purity
99.51
Solubility
H2O
Storage Conditions
Store at -80°C for 2 years
Shipping Conditions
Dry Ice

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0202068-01	1 mgQM-0202068-01 £451.65/ea	£0.00	Quantity	£451.65/ea	£0.00

5 mgQM-0202068-02	5 mgQM-0202068-02 £1,016.63/ea	£0.00	Quantity	£1,016.63/ea	£0.00

10 mgQM-0202068-03	10 mgQM-0202068-03 £1,581.60/ea	£0.00	Quantity	£1,581.60/ea	£0.00

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KY-1044 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.