L-054522 [CAS 214348-67-1]

L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM) [1].

[214348-67-1]

C35H47N7O5

645.79

O=C([C@H](CCCCN)NC([C@@H]([C@@H](C)C1=CNC2=C1C=CC=C2)NC(N3CCC(CC3)N4C5=CC=CC=C5NC4=O)=O)=O)OC(C)(C)C

Somatostatin Receptor

Room temperature