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L-745870 [CAS 158985-00-3]

L-745870 [CAS 158985-00-3]

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SKU:QM-0147919-01

£106.00 GBP
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  • Description

    L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3].

  • CAS Number

    [158985-00-3]

  • Molecular Formula

    C18H19ClN4

  • Molecular Weight

    326.82

  • Smiles

    ClC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43

  • Target

    Dopamine Receptor

  • Isoform

    D2 Receptor; D3 Receptor; D4 Receptor

  • Purity

    99.92

  • Solubility

    DMSO : 25 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0147919-01
5 mgQM-0147919-01
£106.00/ea
£0.00
£106.00/ea £0.00
10 mM - 1 mLQM-0147919-02
10 mM - 1 mLQM-0147919-02
£115.00/ea
£0.00
£115.00/ea £0.00
10 mgQM-0147919-03
10 mgQM-0147919-03
£200.66/ea
£0.00
£200.66/ea £0.00
50 mgQM-0147919-04
50 mgQM-0147919-04
£527.50/ea
£0.00
£527.50/ea £0.00
100 mgQM-0147919-05
100 mgQM-0147919-05
£740.12/ea
£0.00
£740.12/ea £0.00

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L-745870 [CAS 158985-00-3]

L-745870 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.