L-Methionine-DL-sulfoximine [CAS 15985-39-4]
L-Methionine-DL-sulfoximine [CAS 15985-39-4]
SKU:QM-0160013-01
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Product Details
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Description
L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) [1][2][3][4][5].
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CAS Number
[15985-39-4]
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Molecular Formula
C5H12N2O3S
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Molecular Weight
180.23
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Smiles
O=C(O)[C@@H](N)CCS(=N)(C)=O
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Target
Glutaminase
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Purity
98
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Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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L-Methionine-DL-sulfoximine [CAS 15985-39-4]
L-Methionine-DL-sulfoximine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.