L-p-Boronophenylalanine [CAS 76410-58-7]
L-p-Boronophenylalanine [CAS 76410-58-7]
SKU:QM-0190604-01
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Product Details
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Description
L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2) . L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT) . When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma[1][2].
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CAS Number
[76410-58-7]
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Molecular Formula
C9H12BNO4
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Molecular Weight
209.01
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Smiles
O=C(O)[C@@H](N)CC1=CC=C(B(O)O)C=C1
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Target
Biochemical Assay Reagents
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Purity
99.84
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Solubility
1 M HCl : 10 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCl; heat to 60°C) |DMSO : 10.94 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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L-p-Boronophenylalanine [CAS 76410-58-7]
L-p-Boronophenylalanine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.