L-R4W2 [CAS 206350-79-0]

L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic[1][2].

[206350-79-0]

C46H71N21O6

1014.19

O=C(N)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)=O)=O

TRP Channel

TRPV1

H2O

Room temperature