Lanuginosine is an alkaloid. Lanuginosine can be isolated from the stems of Xylopia laevigata (Annonaceae) and the leaves of Magnolia grandiflora. Lanuginosine induces Apoptosis. Lanuginosine inhibits AChE (IC50: 10.9 μM) . Lanuginosine inhibits Aβ aggregation. Lanuginosine exhibits anticancer activity against hepatocellular carcinoma, human promyelocytic leukemia, human chronic myeloid leukemia, melanoma, and brain tumors. Lanuginosine can be used in the research of Alzheimer's disease[1][2][3].
CAS Number
[23740-25-2]
Molecular Formula
C18H11NO4
Molecular Weight
305.28
Smiles
O=C1C2=CC(OC)=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53
Target
Amyloid-β; Apoptosis; Cholinesterase (ChE)
Purity
98.27
Solubility
DMSO : 0.5 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCl; heat to 60°C)