Lapatinib-d7 [CAS 1009307-23-6]

Lapatinib-d7 (GW572016-d7) is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

[1009307-23-6]

C29H19D7ClFN4O4S

588.1

[2H]C([2H])([2H])S(C([2H])([2H])C([2H])([2H])NCC1=CC=C(O1)C2=CC(C(NC3=CC(Cl)=C(C=C3)OCC4=CC(F)=CC=C4)=NC=N5)=C5C=C2)(=O)=O

Autophagy; EGFR; Ferroptosis; Isotope-Labeled Compounds

Room temperature