LASSBio-1985

LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies[1].

C18H22N2O7

378.38

O=C(O)C1=CC=C(/C=N/NC([C@]2(O)C[C@@H](O)[C@H](OC(C)(C)O3)[C@H]3C2)=O)C=C1

Parasite

Room temperature