LBG20304

LBG20304 (compound 2s) is a ligand for the homologous GluK5 receptor (IC50: 432 nM), more than 40-fold selective over the homologous GluK1-3 isoforms. Low doses of LBG20304 (10 μM), it exhibits low agonist activity in neuronal slices (rat) [1].

C19H18N4O5

382.37

O=C([C@H]1NC[C@H](N2N=NC=C2C3=CC=C4C=C(O)C=CC4=C3)[C@@H]1CC(O)=O)O

IGluR

Room temperature