LC-PDin06 [CAS 2027514-32-3]

LC-PDin06 is a selective PRDX1 inhibitor with an IC50 of 0.042 μM. LC-PDin06, a Celastrol derivative, shows potent antiproliferative activity against colorectal cancer cells by significantly increasing ROS levels[1].

[2027514-32-3]

C35H47N3O3

557.77

OC1=C(C)C2=CC=C3[C@@]4(C)CC[C@@]5(C)CC[C@@](C)(C(NCCCN6C=CN=C6)=O)C[C@]([H])5[C@@](C)4CC[C@](C)3C2=CC1=O

Reactive Oxygen Species (ROS)

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