LD-38 [CAS 3094583-35-1]

LD-38 is a drug-linker conjugate for ADC. LD-38 consists of a topoisomerase 1 inhibitor (Exatecan) and a highly hydrophilic stable and cleavable linker. LD-38 can be used for synthesis of ADC[1][2].

[3094583-35-1]

C67H87FN10O20S

1403.53

O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C(NC2=CC=C(COC(N[C@H]3CCC(C(C)=C(F)C=C4N=C5C6=CC7=C8COC([C@](CC)7O)=O)=C4C3=C5CN6C8=O)=O)C=C2)=O)CCC(NCC[N+](C)(CCCS([O-])(=O)=O)C)=O)=O)=O)=O

Drug-Linker Conjugates for ADC; Topoisomerase

Topo I

Room temperature