LDN-211904 [CAS 1198408-39-7]

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SKU:QM-0145518

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Product Details

Description
LDN-211904 is a potent and reversible EphB3 inhibitor with an IC50 of 79 nM. LDN-211904 shows good metabolic stability in mouse liver microsomes. LDN-211904 with cetuximab could be effective in inhibiting STAT3-activated colorectal cancer (CRC) stemness and Cetuximab resistance in CRC[1][2].
CAS Number
[1198408-39-7]
Molecular Formula
C19H19ClN4O
Molecular Weight
354.83
Smiles
O=C(C1=CN=C2C=CC(C3CCNCC3)=CN21)NC4=C(Cl)C=CC=C4
Target
Ephrin Receptor
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H319-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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LDN-211904 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.