LE 300 [CAS 274694-98-3]

LE 300 is a potent and selective dopamine D1-like receptor antagonist with Kis of 1.9 nM and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively. LE 300 is an antagonist of the 5-HT2A receptor with a pA2 of 8.32 in a rat tail artery assay[1][2].

[274694-98-3]

C20H22N2

290.4

CN1CCC2=C(NC3=C2C=CC=C3)CC4=CC=CC=C4CC1

5-HT Receptor; Dopamine Receptor

5-HT2 Receptor; D1 Receptor; D5 Receptor; α-1 microglobulin

98.5

DMSO : 29.04 mg/mL (ultrasonic; warming)

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice