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LEB-03-145 [CAS 2858812-90-3]

LEB-03-145 [CAS 2858812-90-3]

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QM-0065254

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Product Details

  • Description

    LEB-03-145 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a C5 alkyl linker[1].

  • CAS Number

    [2858812-90-3]

  • Molecular Formula

    C45H55N11O6

  • Molecular Weight

    845.99

  • Smiles

    C=CCN1C(C2=C(N1C3=NC(C(C)(O)C)=CC=C3)N=C(N=C2)NC4=CC=C(C=C4)N5CCN(CC5)CCCCCNC(CCC6=CC=C(O6)N7CCN(CC7=O)C(C=C)=O)=O)=O

  • Target

    Wee1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature
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1 EachQM-0065254
1 EachQM-0065254
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LEB-03-145 [CAS 2858812-90-3]

LEB-03-145 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.