Lenalidomide-acetylene-C5-COOH [CAS 2429878-72-6]
Lenalidomide-acetylene-C5-COOH [CAS 2429878-72-6]
SKU:QM-0142910-01
Couldn't load pickup availability
Request quote or documents
![Lenalidomide-acetylene-C5-COOH [CAS 2429878-72-6]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1]. Lenalidomide-acetylene-C5-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
CAS Number
[2429878-72-6]
-
Molecular Formula
C21H22N2O5
-
Molecular Weight
382.41
-
Smiles
O=C1N(C2C(NC(CC2)=O)=O)CC3=C1C=CC=C3C#CCCCCCC(O)=O
-
Target
E3 Ligase Ligand-Linker Conjugates
-
Isoform
Cereblon
-
Purity
99.26
-
Solubility
DMSO : 115 mg/mL (ultrasonic)
-
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H302, H315, H319, H335
-
Precautions
H302, H315, H319, H335
Related Products
- QM-0054857-01 α-Ketoglutaric acid (disodium dihydrate) [CAS 1282616-74-3]
- QM-0054003 δ-Hexachlorocyclohexane-13C6
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052819-01 Zolpidem phenyl-4-carboxylic acid ethyl ester-d6 [CAS 1216455-48-9]
- QM-0052711 α-D-Glucopyranoside, 2-chloro-4-nitrophenyl, 2,3,4,6-tetraacetate [CAS 153823-58-6]
- QM-0052492-01 α-D-Galactopyranose,2- (acetylamino) -2-deoxy-,1,3,4,6-tetraacetate [CAS 10385-50-9]
- QM-0051894-01 β-D-Glucopyranoside,2-bromoethyl,2,3,4,6-tetraacetate [CAS 16977-78-9]
- QM-0051893 β-D-Glucopyranoside,2-chloro-4-nitrophenyl,2,3,4,6-tetraacetate [CAS 35023-71-3]
- QM-0051820-01 β-D-Glucopyranuronic acid, methyl ester,1,2,3,4-tetrakis (2-methylpropanoate) [CAS 150607-94-6]
- QM-0051622-01 α-Ketoglutaric acid (disodium hydrate)
Other industry favorites
- QM-0054857-01 α-Ketoglutaric acid (disodium dihydrate) [CAS 1282616-74-3]
- QM-0054003 δ-Hexachlorocyclohexane-13C6
- QM-0206023-01 α-Demethylnaproxen [CAS 23981-47-7]
- QM-0203548-01 α-Acetobromo-D-xylose, 95% [CAS 3068-31-3]
- QM-0071124 β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5- (4-methylbenzoate) [CAS 1884324-98-4]
- QM-0131262 [Thr28, Nle31]-Cholecystokinin (25-33), sulfated [CAS 77568-41-3]
- QM-0023392 α-Mycolic acid, keto cis [CAS 2260795-20-6]
- QM-0022881 [R- (Z) ]-4-Amino-3-chloro-2-pen-tenedioicacid [CAS 90288-29-2]
- QM-0167516 α-D-Glucopyranoside, methyl 4-deoxy-4-fluoro,2,3,6-tribenzoate [CAS 84065-98-5]
- QM-0166583-01 β-D-Galactosyl- (1→3) -N-acetyl-D-galactosamine [CAS 3554-90-3]
Lenalidomide-acetylene-C5-COOH [CAS 2429878-72-6]
Lenalidomide-acetylene-C5-COOH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.