[Leu15]-Gastrin I (human) [CAS 39024-57-2]

[Leu15]-Gastrin I (human) is a Gastrin I, human peptide hormone derivative, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer[1][2][3][4].

[39024-57-2]

C98H126N20O31

2080.16

O=C([C@H]1N(CCC1)C(CNC([C@H]2NC(CC2)=O)=O)=O)N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78

Cholecystokinin Receptor

99.98

DMSO : 100 mg/mL (ultrasonic) |H2O : 10.53 mg/mL (ultrasonic; adjust pH to 11 with NaOH)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Blue Ice