Levetiracetam [CAS 102767-28-2]

Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent[1][2].

[102767-28-2]

C8H14N2O2

170.21

NC([C@@H](N(CCC1)C1=O)CC)=O

DNA Methyltransferase

99.98

DMSO : ≥ 85 mg/mL|H2O : ≥ 85 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H319

H302, H319