LH2-051 [CAS 2358754-22-8]

Name: LH2-051 [CAS 2358754-22-8]
Brand: QuantiMol
SKU: QM-0153216-01
Price: 301.5 GBP
Availability: InStock

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SKU:QM-0153216-01

£301.50 GBP

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Product Details

Description
LH2-051, a lysosome-enhancing compound (LYEC), is a brain-penetrant dopamine transporter (DAT) inhibitor (Ki: 0.95 μM) . LH2-051 inhibits DAT-mediated dopamine uptake with an IC50 of 3.0 μM. LH2-051 promotes nuclear translocation of TFEB and lysosome biogenesis. LH2-051 improves the memory of amyloid precursor protein (APP) /Presenilin 1 (PS1) mice. LH2-051 can be used for the study of Alzheimer’s disease[1].
CAS Number
[2358754-22-8]
Molecular Formula
C27H34N2O3
Molecular Weight
434.57
Smiles
COC1=C(OC)C=C(C(CCC2=CNC3=C2C=CC=C3)N(CC4CCOCC4)CC5)C5=C1
Target
CDK; Dopamine Transporter
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, stored under nitrogen)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0153216-01	5 mgQM-0153216-01 £301.50/ea	£0.00	Quantity	£301.50/ea	£0.00

10 mgQM-0153216-02	10 mgQM-0153216-02 £458.24/ea	£0.00	Quantity	£458.24/ea	£0.00

25 mgQM-0153216-03	25 mgQM-0153216-03 £803.30/ea	£0.00	Quantity	£803.30/ea	£0.00

50 mgQM-0153216-04	50 mgQM-0153216-04 £1,179.95/ea	£0.00	Quantity	£1,179.95/ea	£0.00

100 mgQM-0153216-05	100 mgQM-0153216-05 £1,744.92/ea	£0.00	Quantity	£1,744.92/ea	£0.00

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LH2-051 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.