Ligustroflavone [CAS 260413-62-5]
Ligustroflavone [CAS 260413-62-5]
SKU:QM-0162856-01
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Product Details
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Description
Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis[1][2][3].
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CAS Number
[260413-62-5]
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Molecular Formula
C33H40O18
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Molecular Weight
724.66
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Smiles
O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO[C@H](O[C@@H](C)[C@H](O)[C@H]3O)[C@@H]3O)[C@@H](O)[C@@H]4O)[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)=C6)C2=C6O
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Target
CaSR; Mixed Lineage Kinase; RIP kinase; TGF-beta/Smad
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Isoform
RIPK1; RIPK3
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Purity
99.9
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319
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Precautions
H302, H315, H319
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Ligustroflavone [CAS 260413-62-5]
Ligustroflavone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.