Lintitript [CAS 136381-85-6]

Lintitript (SR 27897) is a highly potent, selective, orally active, competitive and non-peptide cholecystokinin (CCK1) receptor antagonist with an EC50 of 6 nM and a Ki of 0.2 nM. Lintitript displays > 33-fold selectivity more selective for CCK1 than CCK2 receptors (EC50 value of 200 nM) . Lintitript increases plasma concentration of leptin and food intake as well as plasma concentration of insulin[1][2][3].

[136381-85-6]

C20H14ClN3O3S

411.86

O=C(O)CN1C(C(NC2=NC(C3=CC=CC=C3Cl)=CS2)=O)=CC4=C1C=CC=C4

Cholecystokinin Receptor

CCKAR

99.58

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H301, H318

H301, H318