Lipid N2-3L [CAS 2924606-55-1]
Lipid N2-3L [CAS 2924606-55-1]
SKU:QM-0008859
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Product Details
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Description
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that can be used to generate supramolecular lipid nanoparticles (SMLNPs) for mRNA delivery. Lipid nanoparticles formed by encapsulating a luciferase reporter gene with Lipid N2-3L were detected to accumulate in the lymph nodes of mice, indicating that they can effectively enter the mouse immune system. Lipid nanoparticles formed by encapsulating ovalbumin mRNA and the TLR7/8 agonist Resiquimod with Lipid N2-3L were able to reduce tumor volume and increase survival in the MC-38-OVA mouse colon cancer model. Lipid N2-3L can be used in the research of drug delivery for cancer-related therapies[1].
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CAS Number
[2924606-55-1]
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Molecular Formula
C48H93N3O8
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Molecular Weight
840.27
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Smiles
OCCN(CCO)CCCNC(OCCN(CCOC(CCCCCCC/C=C\CCCCCCCC)=O)CCOC(C(CCCCCC)CCCCCCCC)=O)=O
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Target
Liposome
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Shipping Conditions
Room temperature
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Lipid N2-3L [CAS 2924606-55-1]
Lipid N2-3L is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.