Lipoxin A4 [CAS 89663-86-5]
Lipoxin A4 [CAS 89663-86-5]
SKU:QM-0058788
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Product Details
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Description
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA) -mediated IL-8 release with an IC50 value of 25.74 nM[3].
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CAS Number
[89663-86-5]
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Molecular Formula
C20H32O5
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Molecular Weight
352.47
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Smiles
CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O
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Target
Endogenous Metabolite; Interleukin Related
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Isoform
Human Endogenous Metabolite; IL-6; IL-8
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Concentration
283.71 μM * 250 μL in Ethanol
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Purity
98
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Solubility
10 mM in DMSO
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Storage Conditions
Solution, -20°C, 1 year
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Shipping Conditions
Dry Ice
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Hazard Statement
H225, H319
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Precautions
H225, H319
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Lipoxin A4 [CAS 89663-86-5]
Lipoxin A4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.