1 1

LJI308 [CAS 1627709-94-7]

LJI308 [CAS 1627709-94-7]

Size

QM-0155476-01

£226.18 GBP
Sale Sold out

Request quote or documents

View full details

Product Details

  • Description

    LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation[1][2].

  • CAS Number

    [1627709-94-7]

  • Molecular Formula

    C21H18F2N2O2

  • Molecular Weight

    368.38

  • Smiles

    OC1=C(C=C(C=C1F)C2=C(C=CN=C2)C3=CC=C(C=C3)N4CCOCC4)F

  • Target

    Ribosomal S6 Kinase (RSK) ; YB-1

  • Isoform

    RSK2; RSK3

  • Purity

    99.07

  • Solubility

    DMSO : 25 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
Learn more
Variant Variant total Quantity Price Variant total
5 mgQM-0155476-01
5 mgQM-0155476-01
£226.18/ea		 £0.00
£226.18/ea £0.00
10 mM - 1 mLQM-0155476-02
10 mM - 1 mLQM-0155476-02
£243.19/ea		 £0.00
£243.19/ea £0.00
10 mgQM-0155476-03
10 mgQM-0155476-03
£351.32/ea		 £0.00
£351.32/ea £0.00
25 mgQM-0155476-04
25 mgQM-0155476-04
£702.46/ea		 £0.00
£702.46/ea £0.00
50 mgQM-0155476-05
50 mgQM-0155476-05
£1,159.30/ea		 £0.00
£1,159.30/ea £0.00
100 mgQM-0155476-06
100 mgQM-0155476-06
£1,933.25/ea		 £0.00
£1,933.25/ea £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

LJI308 [CAS 1627709-94-7]

LJI308 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.