LLC1

LLC1 is an Amiloride derivative with cytotoxicity against breast cancer cells, particularly those resistant to treatment. The IC50 values of LLC1 for MCF7, MCF7 MX-100, MCF7 TS, MCF7 TR-1, and MCF7 TR-5 are 13, 12, 25, 26, and 19 mM, respectively. LLC1 shows potential for research in the field of cancer therapy[1].

C17H19ClFN7O

391.83

N/C(N)=N\C(C1=C(N=C(C(Cl)=N1)N2CCC(CC2)C3=CC=C(C=C3)F)N)=O

Drug Derivative

Room temperature