LNK01004 [CAS 2445500-24-1]

LNK01004 is a JAK inhibitor with strong inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50:TYK2 (IC50: 1.0 nM) . LNK01004 can simultaneously inhibit multiple cytokine-induced p-STAT signaling pathways. LNK01004 can be used in the research of diseases such as atopic dermatitis[1].

[2445500-24-1]

C26H31N7O2

473.57

N#CCNC(C1=CC=C(C2=NC(NC3=CN(C4CC(C)(C)OC(C)(C4)C)N=C3)=NC=C2C)C=C1)=O

JAK; STAT

Room temperature