LO-3-63

Name: LO-3-63
Brand: QuantiMol
SKU: QM-0012914-01
Price: 614.98 GBP
Availability: InStock

Size 5 mg 10 mg 25 mg 50 mg 100 mg

SKU:QM-0012914-01

£614.98 GBP

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Quote Datasheet SDS COA

Product Details

Description
LO-3-63, a Ribociclib analog bearing a truncated fumaramide handle, is a PROTAC-like CDK4/6 degrader. LO-3-63 induces CUL4DCAF16-dependent degradation of CDK4/6 in cells[1].
Molecular Formula
C32H35ClN10O3
Molecular Weight
643.14
Smiles
O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(C(/C=C/C(NC5=CC(Cl)=CN=C5)=O)=O)CC4)C=C3)N=C2N1C6CCCC6)N(C)C
Target
CDK; E1/E2/E3 Enzyme
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0012914-01	5 mgQM-0012914-01 Regular price ~~£418.50~~ Sale price £614.98/ea	£0.00	Quantity	Regular price ~~£418.50~~ Sale price £614.98/ea	£0.00

10 mgQM-0012914-02	10 mgQM-0012914-02 Regular price ~~£622.80~~ Sale price £890.78/ea	£0.00	Quantity	Regular price ~~£622.80~~ Sale price £890.78/ea	£0.00

25 mgQM-0012914-03	25 mgQM-0012914-03 Regular price ~~£1,116.00~~ Sale price £1,556.60/ea	£0.00	Quantity	Regular price ~~£1,116.00~~ Sale price £1,556.60/ea	£0.00

50 mgQM-0012914-04	50 mgQM-0012914-04 Regular price ~~£1,766.70~~ Sale price £2,435.05/ea	£0.00	Quantity	Regular price ~~£1,766.70~~ Sale price £2,435.05/ea	£0.00

100 mgQM-0012914-05	100 mgQM-0012914-05 Regular price ~~£2,649.60~~ Sale price £3,626.96/ea	£0.00	Quantity	Regular price ~~£2,649.60~~ Sale price £3,626.96/ea	£0.00

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LO-3-63 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.