Lobeglitazone (sulfate) [CAS 763108-62-9]
Lobeglitazone (sulfate) [CAS 763108-62-9]
SKU:QM-0150010-01
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Product Details
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Description
Lobeglitazone sulfate is a new type of thiazolidinedione. Lobeglitazone sulfate is the orally active agonist for PPAR with EC50 of 137.4 nM and 546.3 nM for PPARγ and PPARα. Lobeglitazone sulfate is the inhibitor for ERK/JNK/Smad/NF-κB signaling pathway. Lobeglitazone sulfate exhibits anti-inflammatory, anti-diabetic, anti-fibrotic and anti-atherosclerotic properties[1][2][3][4][5][6].
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CAS Number
[763108-62-9]
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Molecular Formula
C24H26N4O9S2
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Molecular Weight
578.61
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Smiles
O=C(SC1CC2=CC=C(C=C2)OCCN(C)C3=NC=NC(OC4=CC=C(C=C4)OC)=C3)NC1=O.O=S(O)(O)=O
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Target
COX; ERK; Interleukin Related; JNK; NF-κB; NO Synthase; PPAR; TGF-beta/Smad
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Isoform
PPARα; PPARγ
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Purity
99.63
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Lobeglitazone (sulfate) [CAS 763108-62-9]
Lobeglitazone (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.