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Lonafarnib [CAS 193275-84-2]

Lonafarnib [CAS 193275-84-2]

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SKU:QM-0150497-01

£200.66 GBP
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  • Description

    Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

  • CAS Number

    [193275-84-2]

  • Molecular Formula

    C27H31Br2ClN4O2

  • Molecular Weight

    638.82

  • Smiles

    O=C(N1CCC(CC(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N

  • Target

    Autophagy; Farnesyl Transferase; Ras

  • Purity

    99.85

  • Solubility

    DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0150497-01
5 mgQM-0150497-01
£200.66/ea
£0.00
£200.66/ea £0.00
10 mgQM-0150497-02
10 mgQM-0150497-02
£288.14/ea
£0.00
£288.14/ea £0.00
10 mM - 1 mLQM-0150497-03
10 mM - 1 mLQM-0150497-03
£307.58/ea
£0.00
£307.58/ea £0.00
25 mgQM-0150497-04
25 mgQM-0150497-04
£527.50/ea
£0.00
£527.50/ea £0.00
50 mgQM-0150497-05
50 mgQM-0150497-05
£803.30/ea
£0.00
£803.30/ea £0.00
100 mgQM-0150497-06
100 mgQM-0150497-06
£1,179.95/ea
£0.00
£1,179.95/ea £0.00

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Lonafarnib [CAS 193275-84-2]

Lonafarnib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.