Lp (a) -IN-5 [CAS 2924841-79-0]

Lp (a) -IN-5 (Compound A) is an orally active lipoprotein (a) (Lp (a) ) inhibitor. Lp (a) -IN-5 inhibits the assembly of Apo (a) and ApoB proteins with an IC50 value of 0.41 nM. Lp (a) -IN-5 is promising for research of diseases related to elevated plasma Lp (a) levels, such as cardiovascular diseases[1].

[2924841-79-0]

C43H56N4O7

740.93

O=C(O)[C@H]([C@H]1CCNC1)CC2=CC=CC(CN(CC3=CC(C[C@H](C(O)=O)[C@H]4CCNC4)=CC=C3)CCOC5=CC(C[C@H](C(O)=O)[C@H]6CCNC6)=CC=C5)=C2

Apolipoprotein

Room temperature