LSD1-IN-13 [CAS 2170212-33-4]

LSD1-IN-13 (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 induces differentiation of AML (acute myeloid leukemia) cell lines[1].

[2170212-33-4]

C23H29N3O2S

411.56

O=S(N1CCC2=C1C=CC([C@H]3[C@H](NCC4CCNCC4)C3)=C2)(C5=CC=CC=C5)=O

Histone Demethylase

KDM1/LSD1

10 mM in DMSO

Room temperature